With increasing syndecan-1 quartile more patients went to the ICU post-PCI (Q1 to 4: 3%, 3%, 8% and 11%, P = 0.027) and more patients died (30-day all-cause mortality Q1 to 4: 3%, 3%, 5% and 12%, P <0.002 and long-term all-cause mortality Q1 to 4: 9%, 10%, 12% and 23%, P <0.004) or were admitted with HF (30-day HF Q1 to 4: 2%, 5%, 6% and 10%, P = 0.008 and long-term HF Q1 to 4: 6%, 11%, 13% and 15%, P = 0.015) (data not shown). The gene discussed is SDC1; the disease is hydrops fetalis.