Other examples are the alterations in striatal neuropeptide mRNA produced by repeated administration of L-DOPA, ropinirole or bromocriptine which appeared to correlate with dyskinesia induction in MPTP-treated marmosets [116], the tolerance to diazepam after chronic use [117], and the onset of hyperalgesia by opioid treatment [118]. Here, NPS is linked to drug-induced dyskinesia.