DPP4 and Hypoglycemia: A previous pooled analysis[18] reported that the overall incidence of AEs was similar between sitagliptin (100 mg/day) and other diabetic-comparator agents (except for other DPP-4 inhibitors), including placebos, pioglitazone, metformin, sulfonylureas, sulfonylureas + metformin, and metformin + rosiglitazone (overall side effects: 63.0% vs. 62.8%, hypoglycemia: 3.4% vs. 10.9%).