Combined treatment of γ-tocotrienol with PPARγ agonists, rosiglitazone, and troglitazone was found to be statistically antagonistic on MCF-7 (Figure 4(a)) and MDA-MB-231 (Figure 4(b)) breast cancer cell growth, as evidenced by the location of the data point in the isobologram being well above the line defining additive effect. Here, PPARG is linked to breast carcinoma.