The serum Klotho level was also found to be a significantly independent predictor of baPWV≥1400 cm/sec in a CKD model that included eGFR, albuminuria and hemoglobin as other parameters (Table 2, middle panel) and a CKD-MBD model that included serum calcium, phosphate, intact PTH, 1,25D and FGF23 as other parameters (Table 2, lower panel). This evidence concerns the gene KL and chronic kidney disease.