VEGFA and Miyoshi myopathy: It may well be that in active MM, plasma cells secrete VEGF and FGF-2 that induce inflammatory cells to secrete their own VEGF, FGF-2, and hepatocyte growth factor (HGF); all these cytokines continuously recruit and activate MM-associated macrophages to adapt functionally, phenotypically, and morphologically to become vicarious MMECs, mimicking these cells, and collaborating with them in vessel formation [18].