Results of linear trend test show significant difference in %LWC (P < 0.001), %HTN (P = 0.006), %HTG (P = 0.001), BMI (P < 0.001), WC (P < 0.001), HC (P = 0.002), diastolic blood pressure (P = 0.002), fasting glucose (P < 0.001), HbA1C (P = 0.001), adiponectin level (P = 0.006), triglyceride level (P = 0.01), and cholesterol level (P = 0.03), but no statistical difference in family history of type 2 diabetes, gender ratio, %LHDL, and dose of metformin and gliclazide taken among quartiles of HOMA index. The gene discussed is ADIPOQ; the disease is hypertensive disorder.