Moreover, TZDs, and other PPAR-agonists, such as the prostanoid 15d-PGJ2 [97], induce a variety of favorable changes (growth arrest, apoptosis, and/or partial redifferentiation) in several malignancies, including liposarcoma, and cancers of the breast, colon, pancreas, and prostate [98–101]. Here, PPARA is linked to cancer.