A study of systemic levels of 120 mediators in allotransplanted patients with acute GVHD, including the chemokines CCL2, CCL3, CCL5, CCL7, CCL8, CCL11, CCL13 and CXCL10 together with other cytokines, soluble receptors and adhesion molecules [82]. Four markers of particular importance were identified as markers of acute GVHD. The gene discussed is CXCL10; the disease is acute graft versus host disease.