HSPA1A and neoplasm: In the Hsp70 family, the stress-inducible heat shock protein Hsp70 (also called Hsp72 or Hsp70-1, encoded by HSPA1A), an ATP-dependent chaperone overexpressed in many tumor types, has emerged as a causative factor in tumorigenesis and is now considered a high quality target for therapeutic intervention aiming at cancer cell chemosensitization [5,10].