XRCC1 and colorectal carcinoma: The majority of epidemiological case-control studies did not find any significant correlation between the XRCC1 399Gln variant and the risk of CRC (23,24,28,29), However, a case-control study carried out on a Taiwanese population found that an increased risk of CRC correlated with the XRCC1 399Arg/Arg genotype when compared with the XRCC1 399Gln in younger subjects (21).