Among the CRC cases, we found the frequency of the XRCC1 genotype to be 48.5% GG (63/130), 28.5% AG (37/130) and 23.0% AA (30/130), while the frequency in the general control population was 50.0% GG (75/150), 20.0% AG (30/150) and 30.0% AA (45/150). The gene discussed is XRCC1; the disease is colorectal carcinoma.