LAP3 and hepatocellular carcinoma: The processes in HCC consisted of positive regulation of calcium ion transport into the cytosol, cell proliferation, DNA replication, fibroblast proliferation, immune response, microtubule polymerization, protein secretion and specific transcription from RNA polymerase II promoter; regulation of angiogenesis, cell growth, protein metabolism and the Wnt receptor signaling pathway; and negative regulation of endothelial cell differentiation, microtubule depolymerization, peptidase activity and progression through the cell cycle.