Suppression of glucose-stimulated insulin secretion by epinephrine was greater in IUGR+Veh than CON lambs in absolute terms (−173 cf. −47 μU insulin/μgDNA, P = 0.044), but not as a proportion of insulin secretion in the absence of epinephrine (−28.8% cf. −7.8%, P = 0.274). Here, INS is linked to fetal growth restriction.