Additionally, AHR plays a significant role in tumor promotion and progression by deregulation of cell–cell contact and inhibition of apoptosis (Mulero-Navarro et al., 2005; Diry et al., 2006; Carvajal-Gonzalez et al., 2009; Chopra et al., 2009; Dietrich and Kaina, 2010). Here, AHR is linked to neoplasm.