Nevertheless, the effect of CD44 expression on malignant neoplasms still demonstrates conflicting results, some paper demonstrated that decreased CD44-expression could influence a worse prognosis for the patient[20,21] in endometrioid carcinoma the CD44-expression was observed and no association was found between the protein expression and clinicopathological features suggesting that CD44-expression predictive prognostic factor[38]. Here, CD44 is linked to cancer.