FOXO3 and hepatocellular carcinoma: Western bolt analysis results revealed that serum deprivation caused decreased phosphorylation ratio of AKT and consequently reduced phosphorylation of FOXO3a in HCC cells in a time-dependently manner (Figure 4F, H, J; phosphorylation ratio of AKT and FOXO3a was not shown, see details in Additional file 1: Figure S1).