To correlate our in vitro findings of increased acinar cell production of IL-6, CXCL2/MIP-2α and CCL2/MCP-1 in response to IL-33 stimulation with their expression in vivo in our experimental model, we assayed these cytokines in the pancreas and lung in ligation-induced acute pancreatitis in mice using ELISA. The gene discussed is IL6; the disease is acute pancreatitis.