KMT2A and acute myeloid leukemia: Since more elaborate studies in pediatric AML with other cytogenetic subtypes including MLL-rearranged types are lacking so far and pediatric AML has distinct cytogenetic and clinical features compared to their adult counterparts, we performed expression profiling of 102 pediatric AML samples with distinct cytogenetic subtypes (Table 1) using a quantitative miRNA microarray approach.