Age (60.4±13.5 versus 57.8±14.4 years, P = 0.026), prevalence of diabetes (58.8 versus 47.8%, P = 0.01), serum log10CRP level (−0.79±0.79 versus −0.95±0.71 mg/dL, P = 0.022), D/P cr at 4 h (0.72±0.18 versus 0.64±0.16, P<0.001), and peritoneal Kt/V (1.5±0.6 versus 1.4±0.5, P = 0.044) were significantly higher, while serum triglyceride (137.3±85.5 versus 163.9±95.2 mg/dL, P = 0.001) and albumin levels (2.9±0.5 versus 3.4±0.5 g/dL, P<0.001), and nPCR (0.95±0.24 versus 1.01±0.27 g/Kg/day, P = 0.004) were significantly lower in the high PrCl group compared to the low PrCl group. The gene discussed is ALB; the disease is diabetes mellitus.