In contrast to data from Hagau et al[35], our data suggests that CRP alone may not be an accurate marker for excess cytokine production in severe A(H1N1)pdm09 infection, as levels were similar in both obese and morbidly obese, compared to non-obese, patients on admission to hospital and ICU, despite the increased frequency of pneumonitis in the obese group. This evidence concerns the gene CRP and infection.