INS and type 2 diabetes mellitus: This was mainly reflected in a reduced non-oxidative glucose uptake during insulin infusion in T2D patients (8.4±6.9 vs. 15.4±8.2 μmol/kg/min, p<0.01), although glucose oxidation during insulin infusion was also significantly lower in T2D patients (11.9±3.3 vs. 13.7±3.74 μmol/kg/min, p<0.05).