ITGAD and Cognitive impairment: At acute injury time-points, rats treated with anti-CD11d mAb at 2 h and 24 h after each of three repeated mLFP displayed significant reductions in unconsciousness and self-righting reflex times, cognitive impairments, neutrophil and macrophage levels, astrogliosis, lipid peroxidation, axonal injury, and neuronal loss compared to injured rats treated with a 1B7 control mAb.