CXCL10 and Sepsis: In sepsis patients Trem-1 expression on neutrophils shows a negative correlation to the serum levels of TNF-α (r = −0,63; p < 0,005), IP-10 (r = −0,5; p < 0,035) and procalcitonin (r = −0,59; p < 0,007) (Figure 3).