Despite differences in the absolute methylation level between the two tissues, statistically significant correlations were observed for IGF2 DMR0 and IGF2 DMR2 between blood and tumor tissue among women with invasive breast cancer, indicating that the ranking of individuals with respect to their methylation level is largely preserved in peripheral blood samples from breast cancer patients, but not among women free of breast cancer. This evidence concerns the gene IGF2 and invasive breast carcinoma.