PTGS2 and neoplasm: The presented theranostic PFC nanoemulsion design is innovative in that: 1) It incorporates a selective COX-2 inhibitor; 2) It can serve as a multimodal biological probe for studying the role of COX-2 in macrophage-tumor interaction; and 3) Can be imaged by two complimentary molecular imaging techniques-NIRF and 19F MR.