APOE and atherosclerosis: Because of the increased neutrophil counts observed in hypercoagulable TMPro/Pro:ApoE−/− mice after 35 weeks on a regular chow diet (Table S1C), and the abundant infiltration of neutrophils within vulnerable-appearing atherosclerotic lesions (Figure 4A,C), we explored the impact of hypercoagulability on neutrophil function and hematopoiesis in the context of atherosclerosis.