VWF and coronary artery disorder: A combined analysis of available data yielded adjusted RRs of 1.13 (1.06, 1.21), 1.23 (1.16, 1.32) and 1.16 (1.10, 1.22) per 1 SD higher baseline levels of t-PA antigen (5494 CHD cases), D-dimer (6799 CHD cases) and VWF (6556 CHD cases), respectively (Figure 4).