In the 11 Rosa26-CreERT2: Ssb1−/− mice that developed tumours, we observed a broad tumour spectrum (Figure 8B) including splenic and metastatic B lymphomas, T cell lymphoma in thymus (Figure 8C), hepatocellular carcinoma, (HCC, Figure 8D) and B or T lymphoblastic leukemia (Figure S12). The gene discussed is NABP2; the disease is T-cell non-Hodgkin lymphoma.