Several of the prominent transcription factors in the PCST network, such as nuclear factor (NF)-κB (RELA and REL), activator protein 1 (AP-1; consisting of c-Fos (FOS), c-Jun (JUN), ATF proteins), and CCAAT/enhancer binding protein (C/EBP; family member C/EBP-β (CEBPB)), have been reported to be activated in EGFRvIII-expressing glioblastoma cells in an independent study [58]. The gene discussed is FOS; the disease is glioblastoma.