Serum Ang-1, Ang-2 and Ang-2/Ang-1 were not observed to be significantly associated with age, gender, comorbidities (hypertension, diabetes mellitus or hyperlipidemia), smoking status, time from symptom onset to reperfusion, hemodynamic variables (systolic blood pressure or heart rate) or laboratory observations other than LnNT-proBNP and peak cTnT (data not shown). The gene discussed is NPPB; the disease is hypertensive disorder.