These include: (1) DNA, peptide and protein vaccines to tumor antigens such as HER2 and MUC1, (2) autologous dendritic cell-based vaccines, (3) cytokine therapies, including granulocyte macrophage-colony stimulating factor (GM-CSF), as immune adjuvants, and (4) compounds that block Treg function. The gene discussed is CSF2; the disease is neoplasm.