Additionally, an overexpression of human Hsp40s and significantly increased levels of the anti-DNAJA1 and anti-DNAJA2 antibodies have been found, respectively, in the synovial tissue and sera of RA patients (Kurzik-Dumke et al. 1999; Tukaj et al. 2010a). The gene discussed is DNAJA1; the disease is rheumatoid arthritis.