NR3C1 and asthma: Allele A of the Tth111I NR3C1 gene polymorphism was demonstrated to be an important factor correlating with the risk of development for specific disease phenotypes (severe asthma with ACTTM score ≥20, severe non-allergic asthma with ACTTM score ≥20 and severe allergic asthma with ACTTM score ≥20).