The serum IL-6 level was significantly increased in patients with AE-ILD in theAoDILD state (Table 3, Figure 1B).While the serum TIMP-1 and IL-2Rα levels were significantly increased inpatients with DI-ILD in the AoDILD state (Table 3, Figure1B), TIMP-2, MMP-3, and eotaxin 2 were decreased. Here, TIMP1 is linked to interstitial lung disease.