To find out whether soluble biomarkers inferred from the NASH-associated changes in the adipose tissue’ phosphoproteome using a knowledge-based in silico approach, the levels of FasL and CCL-2 were measured in 37 serum samples previously collected in the course of the ongoing study of NAFLD pathogenesis. The gene discussed is FASLG; the disease is metabolic dysfunction-associated steatohepatitis.