When the definition of skin infection was extended to include abscess or non-abscess infection/dermatitis (Figure 1C, right panels), CREB TG male mice continued to show earlier and more frequent infection than WT male (p<0.0001), but the distinction in female mice between CREB TG and WT was not significant (p = 0.17). This evidence concerns the gene CREB1 and dermatitis.