MAPK14 and neoplasm: Pharmacological inhibition of p38 was also associated with decreased clonogenic survival in MCF-7TN-R cells in vitro and a statistically significant reduction in tumor volume, as compared to vehicle mice, thus indicating that RWJ67657 MAPK inhibition can biologically reverse the aggressive properties seen in MCF-7TN-R cells, in addition to the molecular reversals described above.