ATP8B1 and benign recurrent intrahepatic cholestasis type 1: BRIC is an autosomal recessive disorder (2) caused by the mutation of two hepatic transporter genes: the ATP8B1 gene, coding for familial intrahepatic cholestasis-1 (FIC1; BRIC type 1) and the ABCB11 gene, coding for the bile salt export pump (BSEP; BRIC type 2) (3,4).