CYBB and Stroke: In order to determine if reduced Nox2 protein expression in apocynin-treated rats following stroke was associated with changes in inflammatory cell numbers, light field OX-42 immunohistochemistry was utilized to compare the number of activated microglia/macrophages in the infarct core of the ipsilateral cortex where an equivalent area of damage was demonstrated in both vehicle- (Figure 7(a)) and apocynin-treated rats (Figure 7(b)).