In terms of B-cell NHL subclassification, most MYC-rearranged cases had large cell morphology or a complex karyotype, consistent with DLBCL [14, 19, 22, 23, 26, 31, 50] Two cases (cases 17 and 18) reportedly had monomorphic medium-sized cells, a germinal center immunophenotype (expression of CD10), and a relatively simple background karyotype, suggesting that these cases may represent an unusual extranodal presentation of Burkitt's lymphoma [16, 17]. This evidence concerns the gene MYC and Burkitt lymphoma.