However, in subjects carrying the G allele (CG or GG) for the SEC14L2/TAP gene, the association between the rs1279683 (SLC23A2) polymorphism and POAG risk was lower (unadjusted OR 1.77, 95% CI 1.11–2.84, p=0.016). Here, SEC14L2 is linked to open-angle glaucoma.