We recently reported that in Th1 cytokine enriched microenvironment, MIG/CXCL9 and IP-10/CXCL10 were upregulated while IL-1β and IL-6 were downregulated with concomitant reduction in the percentage of MDSC in a 3D breast cancer model [14]. The gene discussed is CXCL9; the disease is breast carcinoma.