LPIN1 and Hepatic fibrosis: For example, the common variant (rs13412852) influencing the expression of Lipin-1 (LPIN1) [277], was associated with lipid levels, NASH severity, and hepatic fibrosis in children with NAFLD, whereas it influenced body mass, but not the severity of liver histology, in adults with NAFLD of the same ethnicity [278, 279].