Cannabinoid agonist-treated mice challenged with an HF diet exhibited significantly higher CD11c mRNA levels (2.5-fold) than were exhibited after the HF diet alone (Figure 6C), and the serum LPS levels and the F4/80 mRNA levels were similarly affected by the HF-diet treatment (Figures 6A, 6B and 6C). This evidence concerns the gene ITGAX and hydrops fetalis.