ABCC10 and neoplasm: More recently, we conducted in vivo MRP7 overexpressing tumor xenograft nude mouse model study and found that MRP7 transfected tumors are more resistant to paclitaxel, and this resistance can be reversed by nilotinib, a potent reversal agent for MRP7-mediated MDR [51] Our finding therefore warrants clinical studies to test the efficacy of tariquidar in reversing MRP7-mediated MDR in chemotherapy-resistant patients.