Transforming growth factor beta (TGF-β), which is abundantly expressed in many pathological conditions, heavily influence tumor growth and maintenance as the cytokine plays important roles in forming tumor microenvironment, and facilitating angiogenesis (Wojtowicz-Praga, 1997; Zou, 2005; Bierie and Moses, 2006; Sheu et al., 2008). The gene discussed is TGFB1; the disease is neoplasm.