BRMS1 and neoplasm: Although this has complicated the studies regarding molecular mechanisms, BRMS1 has been demonstrated to alter specific cellular pathways associated with metastasis including gap junctional intercellular communication [21]–[23], phosphoinositide signaling [24], [25], nuclear factor kappa B signaling [26]–[29], cell motility and invasion [30]–[32], apoptosis [28], [33], and tumor cell dissemination [33].