HMGB1 and acute respiratory distress syndrome: The median values (IQR) for patients who developed ALI and for patients who did not were 3.69 (0.43-96.0) versus 0.21 (0.07-0.81) for miR-122 (P = 0.002), 2.14 (1.36-4.33) versus 0.54 (0.34-0.86) ng/ml for HMGB1 (P < 0.001), 402.7 (129.0-487.0) versus 159 (126.0-206.0) U/L for apoptosis K18 (P = 0.02), 685.0 (435.0-1098.0) versus 328 (242.0-428.0) U/L for necrosis K18 (P = 0.002), and 33.0 (16.8-61.0) versus 16.3 (12.0-22.0) for GLDH activity (P = 0.03).