The immunohistochemistry staining showed that the tumor cells were diffusely positive for S-100, CD1a, langerin and CD68, but negative for CD3, CD5, CD20, CD21, CD30, CD38, CD56, CD79a, ALK, HMB-45, Melan-A, pan-cytokeratin and MPO. The gene discussed is MLANA; the disease is neoplasm.