Provided this concept is validated under in vivo conditions, our present results would help to explain for example the contribution of senescent cells to age-associated inflammation (inflammaging, see [119]) responsible for age-related inflammatory degenerative diseases, such as atherosclerosis, where the role of inflammatory cytokines [120] and TGFβ[121] has been already reported. This evidence concerns the gene TGFB1 and atherosclerosis.